Study of a Novel Anti-Tubercular Acylhydrazone Schiff Base Derivative

Image Tuberculosis (TB) remains the most serious infectious disease worldwide and predominantly occurs in developing countries. The annual death from TB caused by Multidrug-Resistant (MDR) and Extensively Drug-Resistant (XDR) Mycobacterium Tuberculosis(MTB) outnumbers Human Immunodeficiency Virus (HIV). Especially, 90% of active disease in MDR-TB occurs within the first two years and nearly all within three years, indicating the difficulties of MDR-TB treatment. The traditional anti-TB drugs such asisoniazid, rifampicin, pyrazinamide, ethambutol, streptomycin, kanamycin, amikacin, capreomycin, le... Read More

Overview of Clostridium difficile Infection in Cancer Patients

Image Clostridium difficile Associated Diarrhoea (CDAD) is the leading cause of nosocomial diarrhoea. Clostridium difficile Infections (CDIs) may be induced by medication or medical procedures that disrupt normal bowel flora or interfere with bowel motility. The emergence of hyper-virulent strains of CDI, reports of severe or recurrent CDI in immune competent populations, advent of various infection control challenges, and diagnostic and therapeutic dilemmas have contributed to a shift in the disease paradigm. However, there is insufficient data on the risk of CDI in vulnerable cancer patients re... Read More

Application of Cancer Antigen 125 Test in Diagnosis of Pulmonary Tuberculosis

Image Pulmonary tuberculosis (TB) is a contagious bacterial infection that attacks the lungs and spread to other organs. Globally, tuberculosis remains one of the leading causes of death and public health problems despite dramatic improvements made in providing access to high-quality TB services. WHO estimates that about one third of all incident cases of active TB are not properly diagnosed or receive care of poor quality outside of national TB programs. Among diagnosed cases, the delay of the result is often long. Determination of dise... Read More

Testicular Metastases

Image Metastases to testis are a very rare cause of a testicular mass and may be bilateral in up to 15% of patients.  Epidemiology Metastases to the testes are apparent in ~0.04% of autopsy studies in patients with known malignancy. The average age is 57 years, much older than the primary age for primary ... Read More